solubility and bioavailability improvement
Available from Lonza Pharma & Biotech
Proven bioavailability enhancement technologies
Our bioavailability enhancement technologies include:
Particle size reduction: micronization and nano-milling
Solid dispersion technologies: hot-melt extrusion or spray drying
Lipid / liquid based formulations: liquid-filled hard capsule technology or soft gel approaches
Specialized nanocrystalline dispersion and spray-dried nanoadsorbate technologies
Complementary drug delivery technologies are utilized to modulate pharmacokinetics of the solubilized compound and achieve a full range of absorption profiles.
Our scientists take a data-driven approach to characterizing BA problem statement(s) and selecting the enabling technology to advance your compound.
Our integrated product design and development services provide the full range of capabilities to support the rapid advancement of compounds from concept to clinic. This range of services has been integrated in our SimpliFiH(TM) Solutions offering designed to be phase-appropriate and to simplify your pathway to IND/IMPD studies:
API development and supply
Product design and preformulation development
Formulation and product development
Analytical services and quality control
Clinical trial manufacture
Clinical packaging and supply services
Additionally, our SimpliFiH® Solutions integrated service package is designed specifically to rapidly advance compounds to first-in-human studies.