Analysis of Two API Products Using the Opt-Diss 410 UV FIber Optics with Multi-Component Analysis
Publisher: Distek, Inc.
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This white paper explains the theory behind the MCA algorithm methodology. Then, used in tandem with in-situ fiber optics, the accuracy of the technique is demonstrated by recovering the concentration of two APIs in known mixed solutions. Finally, an example is given of accurately monitoring and quantifying the dissolution profile of an actual commercial product containing two APIs, demonstrating the elimination of the need to draw samples or to perform HPLC analysis for many of these type of products.
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