L.B. Bohle Tablet Coating Technology

Dry granulation, also known as roller compaction, has become a widely used granulation technology in recent years. It has a wide range of applications. Powders are compacted between rotating rollers to form a flake. The flakes are crushed into granules with the desired particle size distribution using a sieve and sieve inserts. The pressed and dried granules are used in various ways in the pharmaceutical industry. Granules can be used as starting materials, intermediates, dosage forms for immediate preparation, and granules for ingestion.

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Tablets are the most important oral dosage form in the pharmaceutical industry. The advantages of tablets are numerous. First and foremost is the ability to precisely control dosage and the high stability of active ingredients. In addition, tablets can be produced quickly and in large quantities and offer flexible design freedom in terms of size, shape, and color. Tablets can be effervescent, dissolving, or dispersible, dissolving tablets, lozenges, or enteric-coated and retarding tablets, as well as uncoated and coated tablets.

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Today, fluid bed drying can still be considered state of the art within pharmaceutical drying processes. With the additional implementation of spray nozzles fluid bed dryers became fluid bed granulators - thus wet granulation could be smoothly performed in one discrete device.

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