Bulk Drug Refining and Evaluation of Physical Properties: Particle size distribution and SEM observation of Ethenzamide
Publisher: Microtrac Inc, Part of Verder Scientific
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In the manufacture of pharmaceuticals, bulk refining of the drug and the control of its physical properties (shape, etc.) are important factors in improving the tablet properties (tensile strength, solubility and consolidation characteristic). Here, we discuss the optimum conditions for jet milling during the manufacture of drug products from ethenzamide (crystalline bulk drug) based on data from particle size distribution measurement and morphological observation under a scanning electron microscope (SEM).
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