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A clinical packaging strategy that can successfully manage the supply of your expensive drug product throughout the duration of clinical testing is critical to the success of sponsor companies. This paper explores six strategies that can be used to maximize a short drug supply for your clinical studies. 1. Employ a drug-sparing strategy 2. Ensure rigorous patient screening and user-friendly packaging 3. Identify accommodating kit design 4. Centralize clinical supply storage 5. Select countries with flexibility in mind 6. Use Just-In-Time Strategies