9/22/20 - Leaderboard - Pharma

The use of Hot-Melt Extrusion (HME) for manufacturing complex drug delivery systems has recently been receiving a lot of interest because it offers a number of advantages over traditional, wet-mass based pharmaceutical manufacturing processes.

With batch sizes as small as 10 grams, the Randcastle Microturder line of small, vertical, single screw lab extruders and recirculating batch mixers are ideal for R&D HME applications where materials are particularly scarce or expensive. Production rates from 5 grams up to 34 kilos/hour are possible. Randcastle’s patented Recirculator Mixing Technology achieves dispersive and distributive mixing similar to horizontal twin-screw HME extruder designs.

Randcastle’s HME technology is suitable for mixing/compounding, granulating, pelletizing, sustained release and thin film pharmaceutical delivery systems forms.

The Randcastle Microtruders range from small-scale ¼” bench-top units for R&D to larger units for production. These units can be supplied with different screw diameters and screw lengths ranging from 35:1 L/D up to 50:1. The output from one unit can feed into another unit to achieve the desired result. For example he output from a recirculating batch mixer can be fed into an extruder.

Electric heaters are used for heating and water jackets are used for cooling.

A wide range of options are also available so the equipment can be supplied to meet your requirements.

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