Cocrystal - Screening Selection, and Formulation Development

Cocrystal - Screening Selection, and Formulation Development

We specialize in cocrystal screening, selection, and formulation development to enhance the performance of your active pharmaceutical ingredients (APIs) by improving their physical and chemical properties. Cocrystals, which are unique crystalline structures composed of multiple components, offer a reliable pathway to address challenges like poor solubility, limited bioavailability, chemical instability, or undesirable melting points. By leveraging our innovative phase diagram-guided approach and an extensive library of over 250 pharmaceutically acceptable coformers, we deliver industry-leading discovery rates of viable cocrystals, enabling significant property enhancements such as increased solubility, optimized dissolution rates, improved stability, and better formulation flexibility. We can also customize our methods, including techniques like wet milling, thermal screening, and solvent grinding, to tailor cocrystal design for your specific needs while also helping to secure intellectual property positions through novel solid-state forms. Our expertise in FDA-aligned regulatory strategies, combined with decades of cutting-edge research, ensures that we transform complex solid-state challenges into actionable solutions for your pharmaceutical products in the shortest timelines possible.