Leaderboard 10.6.2025
Leaderboard 10.6.2025

Triclinic Labs, LLC

Simplifying Complex Chemistry. Insight. Expertise. Solutions.

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At Triclinic Labs, we specialize in solid-state chemical development and materials characterization, providing comprehensive contract research services to support the pharmaceutical, chemical, and materials industries. With nearly four decades of experience, we offer a full range of solutions, including polymorph and salt screening, cocrystal formulation development, crystallization method development, and amorphous materials stability prediction. Our state-of-the-art analytical capabilities include XRPD, electron diffraction, spectroscopy (Raman, FTIR, NMR), chromatography (HPLC, GC, LC-MS), and thermal analysis (DSC, TGA), allowing us to deliver actionable insights on physical and chemical properties, contaminant identification, and drug performance. We also provide intellectual property support, assisting with patent prosecution, litigation, prior art reproduction, and strength assessments to ensure our clients maintain a competitive edge. As an FDA-registered and DEA-licensed lab, we pride ourselves on our flexibility, responsiveness, and ability to tailor solutions to meet your unique needs, whether through cGMP or non-GMP services, all designed to help streamline your development process and safeguard your success. We'll help you derisk your development path!

Company Details

Address
2660 Schuyler Ave, Suite A.
Lafayette, IN 47905

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Products & Services

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Polymorphs and Salts-Screening & Selection

We specialize in providing advanced polymorph screening, salt selection, and chemical property improvement services to...

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Cocrystal - Screening Selection, and Formulation Development

We specialize in cocrystal screening, selection, and formulation development to enhance the performance of your active...

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Non-Crystalline (Amorphous) Materials Characterization, Stability Prediction, Development

We offer specialized characterization and development services for non-crystalline (amorphous) materials, helping you...

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Amorphous Solid Dispersion Development

We specialize in spray drying and amorphous solid dispersion (ASD) development services to enhance the solubility and...

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Crystallization Method Development

We provide comprehensive crystallization method development and optimization services to ensure your active...

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Particle and Habit Engineering

We offer comprehensive particle analysis and materials characterization services to help your business optimize product...

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Chemical Property Improvement & Problem Solving

We specialize in solid-form problem solving and consulting, offering tailored solutions to overcome challenges such as...

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Predictive Materials Modeling

Our Materials Modeling Group leverages advanced computational prediction and design capabilities to guide your product...

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Developing GMP Methods for Solid Analysis

We offer comprehensive cGMP analytical method development, validation, and lot release testing services, specializing...

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Resources & Content

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A Comprehensive Approach for Solid Form Selection in Preclinical Development and Beyond.

A Comprehensive Approach for Solid Form Selection in Preclinical Development and Beyond.

Different solid forms (polymorphs, salts, cocrystals) of an active pharmaceutical ingredient (API) can have very...

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Rapid Development of an Amorphous Solid Dispersion (ASD) – Nifedipine (NIF)

Rapid Development of an Amorphous Solid Dispersion (ASD) – Nifedipine (NIF)

Amorphous solid dispersions (ASD) have long been used to increase the solubility and bi-oavailability of poorly-soluble...

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Microcrystal Electron Diffraction Study of Multi-component Salt and Cocrystal Forms of 3-Nitrobenzoic Acid and Pyrimethanil

Microcrystal Electron Diffraction Study of Multi-component Salt and Cocrystal Forms of 3-Nitrobenzoic Acid and Pyrimethanil

Three single-phase crystals containing 3-nitrobenzoic acid (NBA) and pyrimethanil (PYR) in a 1:1 stoichiometry were...

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Utility of Low Frequency (LF) Raman Mapping: Dissolution of Acetaminophen (ACE) Spray Dried Dispersions (SDD)

Utility of Low Frequency (LF) Raman Mapping: Dissolution of Acetaminophen (ACE) Spray Dried Dispersions (SDD)

This application note outlines the evaluation of post-dissolution ACE SDD. The results indicated that in all of the...

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Cocrystals: A Regulatory Rebirth

Cocrystals: A Regulatory Rebirth

What is the impact of recent changes in FDA guidance on regulatory and intellectual property issues? The FDA...

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In situ observation of Theophylline anhy-drous forms II, III, V, and I* using Variable-Temperature, Variable-Relative Humidity Powder X-ray Diffraction

In situ observation of Theophylline anhy-drous forms II, III, V, and I* using Variable-Temperature, Variable-Relative Humidity Powder X-ray Diffraction

Theophylline was investigated using an Anton Paar Controlled Humidity Chamber (CHC+) attachment on a Rigaku SmartLab...

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Novel Non-Crystalline Materials Analysis: New Strategies to De-risk Amorphous Material Formulation D

Novel Non-Crystalline Materials Analysis: New Strategies to De-risk Amorphous Material Formulation D

The latest approaches for characterizing non-crystalline (amorphous) materials and determining physical stability under...

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Application of Low-Frequency (LF) Raman Spectroscopy to an Isoenergetic Polymorph Study

Application of Low-Frequency (LF) Raman Spectroscopy to an Isoenergetic Polymorph Study

The importance of polymorphism in the pharmaceutical industry is well established. Much literature exists describing...

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News & Press Releases

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Press Release

Triclinic Labs, LLC. introduces new LC/MS and LC/MS/MS Services

Published: 7/31/2025 →
Press Release

Triclinic Labs Appoints Joanna Bis, Ph.D., as Business Development Manager to Expand Client Solutions in Solid-State Chemistry

Published: 7/31/2025 →
Press Release

Triclinic Labs, Inc. and ELDICO Scientific Announce Microcrystal Electron Diffraction Services Partnership.

Published: 6/10/2024 →
Press Release

Triclinic Labs now offers cGMP NMR services with Method Development, Validation, and Release Testing

Published: 4/2/2024 →
Press Release

Triclinic Labs Completes Successful Two-Day Food and Drug Administration Audit

Published: 4/2/2024 →
Press Release

Triclinic Labs, Inc. installs Bruker AVII Ultrashield 400 MHz NMR for both solids and liquids analysis.

Published: 5/11/2020 →

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Cleanroom Equipment > Training Materials & Supplies
Med Rectangle Pharm 2.3.26